Active Psychology & Behaviour Computing & AI

LUMEN: A Feasibility Study of AI-Assisted Dementia Assessment Using Large Language Models, with a Nested Qualitative Evaluation

In plain English

AI plain-English summary

A caregiver sits down with a tablet and answers questions from an AI about their relative’s memory and behaviour, generating a structured report for the memory clinic before the patient’s appointment. This matters because collecting a detailed history from a family member is essential for diagnosing dementia, but it is often rushed, inconsistent, and emotionally draining for caregivers. The LUMEN prototype uses large language models to standardise this conversation, asking clear questions and producing a summary that clinicians can review. The study will test the tool with 20–30 patient-caregiver pairs and 8–10 clinicians in real NHS memory clinics, measuring usability and clinical usefulness through surveys and interviews. If the tool proves feasible and acceptable, it could streamline memory clinic workflows, reduce caregiver burden, and help clinicians reach earlier, more accurate dementia diagnoses. The research is a small-scale feasibility study—it will generate pilot data to support larger trials and future funding applications, not yet change clinical practice.

View original technical description
LUMEN (Large Language Model for Understanding and Monitoring Elderly Neurocognition) is an AI-driven conversational prototype designed to support the dementia diagnostic process by collecting structured collateral histories from caregivers prior to memory clinic assessments. Obtaining detailed and accurate collateral histories is critical for diagnosis but can be inconsistent, time-consuming, and emotionally challenging for caregivers. LUMEN aims to standardise this process, reduce caregiver burden, and enhance diagnostic efficiency by using large language models (LLMs) to guide structured history-taking. This feasibility study with a nested qualitative evaluation will assess LUMEN’s usability, acceptability, and feasibility in real-world clinical settings. We will recruit 20–30 patient-caregiver dyads, with caregivers using LUMEN to generate a collateral history after attending a memory clinic appointment. Usability will be measured using the System Usability Scale (SUS) and National Aeronautics and Space Administration Task Load Index (NASA-TLX), while qualitative semi-structured interviews will explore user experience, accessibility, and barriers to adoption. In parallel, 8–10 clinicians will review LUMEN-generated histories to evaluate their clinical utility, completeness, and relevance. Aligned co-production workshops, held in partnership with community groups to ensure diverse representation, will explore issues around language and culture, refining the tool’s interface, accessibility, and output structure for integration into NHS memory clinics. By exploring feasibility, usability, and clinician perceptions, this study will generate critical pilot data to support future intermediate fellowship applications and larger-scale evaluations. Ultimately, LUMEN has the potential to enhance early dementia diagnosis and streamline memory clinic workflows, making AI-assisted collateral history collection a scalable and clinically viable solution.

View the original record at the funder ↗

Researchers

Judith Harrison (EPMC Awardee)

Related Research

Grants with similar aims, by meaning.

Technical Refinement and Co-Production of the LUMEN Conversational AI Tool for Dementia Assessment
MemoryChat: Developing a Chatbot Tool for Collateral History Taking in Dementia Assessment Using Synthesized Dialogue and Electronic Health Record Data
Improving quality of life for people living with dementia and their care partners: the development, intervention and evaluation of a dementia specific narrative-based intervention: LEND (lived experiences narratives in dementia)
Improving Healthcare Service Assessment through enhancement of Qualitative Research with Large Language Models
Piloting A Secure, Scalable, Infrastructure for AI Dementia Research On Routinely Collected Data

Original classification

Starter Grant for Clinical Lecturers

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