Recipient organisationNIHR Great Ormond Street Biomedical Research Centre
NIHR supportRecorded as supported by this research centre
PeriodFeb 2025 — Feb 2026
In plain English
AI plain-English summary
Children at Great Ormond Street Hospital are being fasted for surgery longer than necessary, and a review of 60,000 patient records aims to find out by how much. Current guidelines allow clear fluids up to one hour before anaesthesia, breast milk up to three hours, and solids up to six hours. Yet studies suggest hospitals often exceed these limits, leaving children without food or drink for far longer. This over-fasting can cause distress, dehydration, and dangerously low blood sugar (hypoglycaemia) in young patients. The exact risk of the condition fasting aims to prevent—pulmonary aspiration—is based on old, variable evidence. By analysing a decade of electronic health records from one of the largest paediatric surgical cohorts in the world, the team will measure actual fasting times against the guidelines. If over-fasting is widespread, the findings could prompt hospitals to tighten scheduling and communication, reducing unnecessary hunger and medical risk for thousands of children undergoing surgery, scans, or treatments each year. The work does not test new fasting rules but provides the real-world data needed to enforce existing ones.
View original technical description
This is a review of patient case notes by the care team with a view to examining current practice for peri-operative fasting for children having general anaesthesia for surgery, therapeutic treatments or diagnostics. Current guidelines for peri-operative fasting at great ormond street are 1 hour for clear fluids, 3 hours for breast milk and 6 hours for formula/ artificial feeding or solids. Children are fasted prior to surgery to reduce the risk of pulmonary aspiration of gastric contents. Evidence for the exact risk of pulmonary aspiration is historic and variable1,2. Nevertheless consensus fasting guidelines for children have been developed and adhered to for many years3. More recently studies have shown that institutional adherence to pre-operative fasting guidelines may result in the over fasting of children prior to general anaesthetic4. Overfasting, has been shown to have adverse effects, including hypoglycaemica on children.5 The primary aim of our study is to evaluate whether children are over-fasted relative to our current guidelines. Over the last 5 years approximately 60000 children have been fasted for elective surgery at GOSH and had their fasting times documented in the electronic healthcare record (EPIC). This provides us with the opportunity to look at peri-operative fasting times in one of the largest cohorts of surgical children in the world.
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