Unknown Brain & Nervous System NIHR-supported project Heart, Stroke & Blood

A study of in-ear electroencephalography signals additionally recorded in hospitalised patients already undergoing standard clinical electroencephalography

In plain English

AI plain-English summary

A hospital patient with impaired consciousness lies wired to a standard scalp EEG, while a soft earplug tucked into their ear canal simultaneously records the same brain activity for the first time. This matters because standard clinical EEG requires a technician to glue roughly 20 electrodes onto the scalp—a time-consuming, uncomfortable process that limits how often and where brain monitoring can happen. Patients with reduced consciousness, hidden seizure activity, or brain dysfunction often need prolonged monitoring, but the current setup makes that impractical outside specialised hospital wards. The researchers have already shown that in-ear EEG works in healthy volunteers during sleep; this pilot study extends that work to the very patients who would benefit most: those already undergoing clinical EEG for impaired consciousness. If the earplug signals match the scalp recordings, the impact could be straightforward: a cheap, unobtrusive device that patients can wear for days at a time, in general wards or even at home, to continuously monitor brain function without a technician present. This would not replace the full clinical EEG for diagnosis, but it could transform how clinicians track recovery, detect hidden seizures, and grade brain dysfunction over time—quietly improving a system most people never think about until they or someone they love is in a hospital bed.

View original technical description
This is a simple pilot study in hospital patients, that builds on our previous research using in-ear electroencephalography (EEG) electrode recordings in healthy people during sleep and in other studies in healthy volunteers. The purpose of this study is to extend this previous work to hospitalised patients who are undergoing a standard clinical EEG as part of the normal standard of clinical care. These are usually patients with impaired conscious level, where EEG can help to detect, grade, and monitor the severity of brain dysfunction, and identify patients who have hidden seizure activity in the brain. A standard clinical EEG safely records the brain’s electrical activity from ~20 electrodes affixed to the scalp by a healthcare technician, but not usually from within the ears. Simultaneously recording the EEG from electrodes in the ear canal will allow us to validate the signals recorded from the ear, i.e., by comparison with the normal signals acquired from the scalp. This comparison will help us learn whether in-ear EEG devices could be useful in practice. We have developed a simple means to record EEG from the ear - in the form of a safe and unobtrusive ‘ear plug’ which has the necessary electrodes built into it, to record electrical currents from the surface of the ear canal.

Researchers

Umesh Vivekananda (Principal Investigator)

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Original classification

Translational Neuroscience

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