Completed Chemistry Materials & Manufacturing

ATLAS - Automated high-throughput platform suite for accelerated molecular systems discovery

In plain English

AI plain-English summary

A robotic laboratory at Imperial College London will automate the synthesis and testing of new materials, running experiments around the clock without human hands. The design space for new materials—from medicines to plastics to battery components—is astronomically large. Testing even a fraction of the possibilities manually would take decades. ATLAS (Automated high-Throughput pLatform Suite) will combine three robotic stations—two for synthesis, one for screening—with automated characterisation equipment that can handle hundreds of samples. Computational modelling will direct which experiments to run, closing the loop between prediction and measurement. If ATLAS works as intended, it will dramatically accelerate the discovery of sustainable polymers, clean energy materials, and new drug formulations. Instead of researchers spending months testing one compound at a time, the platform could screen thousands in parallel, while improving reproducibility by removing human variability. The impact would be felt in manufacturing processes, pharmaceutical supply chains, and energy storage systems—the infrastructure that quietly underpins modern life. This is applied engineering, not fundamental science: the goal is to build a working tool that speeds up materials discovery directly.

View original technical description
The materials design space is too large to be explored empirically. While experimental work can be directed by computational modeling to make this challenge more tenable, the number of tests/syntheses may still be too large on an experimental time-scale. The goal of this project is to combine computational tools (e.g. molecular modelling, process modelling, computer-aided design) and automated HT synthesis and screening platforms to drive and accelerate the discovery and optimisation of new materials. Specifically, ATLAS (Automated high-Throughput pLatform Suite) will comprise three robotic stations dedicated to the synthesis (two platforms) and screening (one platform) of materials. It will be located at Imperial College South Kensington Campus and be paired with materials characterisation equipment able to handle many samples owing to dedicated auto-sampling stations. By executing data-rich experiments, ATLAS will increase the pace of innovation, while enhancing reproducibility. The research enabled by ATLAS will initially target challenges related to the discovery and optimisation of new medicines, sustainable polymers and clean energy materials.

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Researchers

Camille Petit (Principal Investigator)Jerry Heng (Co-Investigator)Rebecca Greenaway (Co-Investigator)Theonitsa (Theoni) Georgiou (Co-Investigator)

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Research Grant

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