NeuroMod+: Co-creation for next-generation neuromodulation therapeutics

A UK network of researchers, clinicians, industry partners, and patients is joining forces to develop brain stimulation treatments that do not require drilling into the skull. Existing neurotechnologies—such as deep brain stimulation for depression or dementia—work, but their invasiveness limits how many people can benefit. Implanting electrodes requires surgery, which carries risks and is not suitable for everyone. The Neuromod+ network aims to solve this by co-creating the next generation of minimally invasive brain stimulation tools. The focus is on technologies that can reach and modulate brain circuits without breaking the skin. If successful, this shift could make bioelectronic treatments for neurological and mental health conditions far more accessible. Instead of a major surgical procedure, a patient might one day receive a treatment that is closer to a routine outpatient intervention. The network also embeds bioethics and policy work from the start, acknowledging that making brain modification technology easier to deploy raises serious societal questions. This is not a single device project; it is a coordination effort to align UK research, industry, and regulation around a common goal. The impact would be a stronger, more responsible UK neurotechnology sector, with global reach.