Completed Public Health & Healthcare Cancer

North West England MRC Fellowships in Clinical Pharmacology and Therapeutics

In plain English

AI plain-English summary

Britain’s supply of doctors trained to develop and test new drugs is running thin, and this scheme aims to train 12 clinical fellows over four years to plug the gap. Clinical Pharmacology—the science of how medicines work in people—was flagged by the government’s Office for Life Sciences as vital for both the NHS and the UK’s pharmaceutical industry. Yet the specialty struggles to attract enough trainees. The programme, run jointly by the Universities of Liverpool and Manchester, tackles that shortage head-on. It builds on the existing MRC Centre for Drug Safety Science and partners with AstraZeneca, GlaxoSmithKline, and two contract research organisations. Fellows will spend time in industry labs as well as academic settings, gaining hands-on experience in drug development, safety testing, and regulation. A particular focus is paediatrics, where children often receive medicines tested only in adults. If successful, the scheme will strengthen the UK’s clinical pharmacology workforce—benefiting healthcare, academic research, drug regulation, and ultimately the training of future doctors. It does not aim to discover a new drug or cure, but to ensure the country has the skilled people needed to do that work in the first place.

View original technical description
In a recent report from the Office for Life Sciences, Clinical Pharmacology was highlighted as a specialty vital for healthcare and industry in the UK. Our proposed scheme builds upon a highly successful training programme in Clinical Pharmacology, based at the University of Liverpool. Our unique selling point is the collaboration between the Universities of Liverpool and Manchester based on the existing MRC Centre for Drug Safety Science, and with 2 pharmaceutical companies (AstraZeneca and GlaxoSmithKline) and 2 contract research organisations (ICON and Medicines Evaluation Unit). We focus on important subject areas, including paediatrics, where there is a fundamental need to improve drugs for children. The scheme is designed to identify the best students, provide them with ?without walls? training through attachments with our industry partners, together with excellent supervision and mentoring arrangements, all of which enhance the student learning experience. Over 4 years, we will train 12 clinical fellows to undertake PhDs; each project will be tailored to the individual and their clinical training. The Clinical Pharmacology skills base in the UK will be enhanced by the scheme with benefit to healthcare, academia, industry, regulation and ultimately undergraduate training.

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Researchers

Munir Pirmohamed (Principal Investigator)

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Original classification

Fellowship

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