Active Psychology & Behaviour Pregnancy, Children & Inherited Conditions

Disorders of attention, awareness and cognitive control

In plain English

AI plain-English summary

Every year, millions of people worldwide—from car crashes, strokes, or battlefield injuries—suffer brain damage that leaves them unable to plan a simple task or pay attention to their surroundings. This matters because acquired brain injury (ABI) is the single biggest cause of long-term disability in the UK, yet the cognitive problems it causes—memory lapses, attention failures, difficulty switching between activities—remain poorly understood and hard to treat. Current rehabilitation often tackles mood and thinking separately, even though they interact. This programme aims to untangle those connections. If successful, the research could produce practical tools: better clinical assessments for common impairments like spatial awareness deficits, and rehabilitation treatments that address planning problems and low activity levels together to improve mood. These would directly change how patients recover daily function after brain injury. The work is applied, not fundamental science. It targets specific, measurable improvements in diagnosis and therapy for a condition that quietly disables millions.

View original technical description
Each year, millions of people around the world suffer an acquired brain injury (ABI). This could be in a road accident, an armed conflict, or from a tumour or stroke. ABIs are the single biggest cause of long-term disability in countries such as the UK and have a high cost for individuals, families and economies. ABIs can have many consequences. Among the most common are problems in cognition (e.g. memory and attention) and mood. This programme is focused on better understanding these difficulties, how they interact, and what they can tell about normal function. It also aims, through this improved understanding, to develop better clinical assessments and practical rehabilitation treatments. Examples include; a) investigating how we move from one activity to another and whether impairments in the necessary processes help us to understand some of the problems faced by people with ABI; b) looking at the relationships between problems in planning and overall activity levels and whether tackling both can improve mood; and c) whether we can develop improved assessments for common post-ABI impairments in spatial awareness and use these to test new treatments.

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Researchers

Fionnuala Murphy (Co-Investigator)Polly Peers (Co-Investigator)Tom Manly (Principal Investigator)

Related Research

Grants with similar aims, by meaning.

Disconnection after traumatic brain injury: impairments of cognitive control and their impact on learning.
UNTANGLE - Understanding how TBI-related changes in fluid biomarkers affect quality of life outcomes in veterans
Dynamic evolution of temporal changes in mild to moderate traumatic brain injury
TRACK-COG-TBI: Imperial Neurotrauma Centre study of clinical outcomes after traumatic brain injury
Understanding how Traumatic Brain Injury - (TBI) -related changes in fluid biomarkers affect quality of life outcomes in veterans. (Untangle)

Original classification

Intramural

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