Active Mental Health NIHR-supported project Psychology & Behaviour

Exploring the cognitive and behavioural mechanisms of Generalised Anxiety Disorder in adolescents: A reflexive thematic analysis (AnDY Research Clinic Project ID: A02)

In plain English

AI plain-English summary

Only half of treated teenagers with Generalised Anxiety Disorder get better, and researchers want to find out why by asking them directly. Current treatments for adolescent GAD are based on models developed for adults, yet the disorder may work differently in young brains. The 53% remission rate after cognitive-behavioural therapy means nearly half of treated adolescents still struggle with anxiety that impairs their schoolwork, friendships, and mental health. This study will interview 11-to-18-year-olds diagnosed with GAD to see whether adult-style mechanisms—such as intolerance of uncertainty, safety-seeking behaviours, and threat beliefs—actually drive their anxiety. It will also explore whether processes like clinical perfectionism, which overlaps with GAD conceptually, play a role in teenagers. If the research identifies distinct cognitive and behavioural patterns in adolescent GAD, it could guide the development of a disorder-specific treatment model tailored to young people. That would give clinicians a clearer target for therapy, potentially raising remission rates beyond the current 53%. The findings are a necessary first step toward interventions that actually match how GAD works in adolescence, rather than retrofitting adult solutions.

View original technical description
Generalised Anxiety Disorder (GAD) is common in adolescents and has a considerable negative impact on psychological, social, and academic functioning. However, existing models and their subsequent treatment approaches have been developed for adults, and little research has explored GAD within clinical populations of adolescents. It is vital to fill this gap, given that current remission rates for GAD in children and adolescents following cognitive-behavioural treatments are reported at just 53%, and therefore greater understanding of the maintenance mechanisms of GAD is needed to develop more effective interventions. In this study, we will use a qualitative approach (semi-structured interviews and reflexive thematic analysis) to explore lived experiences of 11-18 year-olds who have a primary or secondary diagnosis of GAD. We will study whether cognitive and behavioural processes identified in adult models (e.g., intolerance of uncertainty, safety-seeking behaviours and threat beliefs) also feature in experiences of GAD in adolescents. Additionally, we will investigate processes such as clinical perfectionism, which overlap with GAD on a conceptual level, yet have not been assessed in young people with the disorder. Findings will guide the design of future studies, which aim to inform the development of a disorder-specific, developmentally appropriate cognitive model of GAD in adolescents.

Researchers

Polly Waite (Principal Investigator)

Related Research

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Original classification

Mental Health in Development

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