Unknown Psychology & Behaviour NIHR-supported project Pregnancy, Children & Inherited Conditions

Single arm feasibility study to test uptake, retention to the intervention and qualitative process analysis of a family based intervention for mothers at increased risk of breast cancer

In plain English

AI plain-English summary

A mother's weight loss could lower her breast cancer risk, but only if she and her family can stick with the programme. This study tests whether a family-based weight loss intervention is feasible for mothers with overweight or obesity who are at increased risk of breast cancer. Many weight loss programmes fail because they do not account for family dynamics, competing demands, or the social context of eating. The researchers will first review existing evidence and interview families to identify what works and what gets in the way. Then they will run a small trial to measure how many mothers sign up, stay in the programme, and complete it. Patient and public involvement will guide every stage. If the intervention proves feasible, it could lead to a larger trial testing whether family-centred weight loss actually reduces cancer risk in high-risk women. Success would mean shifting from individual diet advice to a model that treats the household as the unit of change. That could make prevention programmes more realistic and effective for women whose cancer risk is shaped by weight, but whose daily choices are shaped by their families.

View original technical description
This is a single arm feasibility study. It aims to examine the feasibility and retention of a family-based weight loss intervention targeting mothers at increased risk of breast cancer who have overweight/obesity aiming to reduce their cancer risk. The intervention design will be informed by a systematic review and a qualitative study which aim to identify successful family intervention components and possible challenges. The intervention design and implementation would also be guided by PPIE activities through out the study phases.

Researchers

Michelle Harvie (Principal Investigator)

Related Research

Grants with similar aims, by meaning.

Systematic review of the effectiveness of family based weight loss interventions compared to non family based/control group interventions at achieving greater weight loss/ dietary and physical activity related behaviour change for mothers with overweight or obesity
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Feasibility Study for a randomised controlled trial of a complex behavioural intervention to reduce weight in obese adults with additional risk factors for chronic disease
Testing the feasibility of a 6:1 intermittent diet breast cancer risk reduction programme to promote healthy eating and prevent weight gain in women at increased risk of breast cancer
Mothers, and health care professionals' views on family support during weight loss for breast cancer prevention

Original classification

Cancer Prevention and Early Detection

Plain English summaries and category classifications on this site are generated by AI and may not perfectly reflect the original research.