Recipient organisationNIHR Moorfields Clinical Research Facility
NIHR supportRecorded as supported by this research centre
PeriodMar 2025 — Dec 2025
In plain English
AI plain-English summary
Twenty-four short-sighted children aged 5 to 12 will wear glasses that shine red light into their eyes for three minutes, twice a day, for three months. This matters because childhood myopia is starting younger and worsening faster than in previous generations, putting many people at risk of permanent vision loss in middle age. Research in China found that twice-daily exposure to low-level red laser light dramatically slowed myopia progression in children, but it is not yet known whether the same treatment works for children in the UK, or whether families here would stick with it. If the trial shows that red-light glasses safely slow eye elongation in children, it could lead to a simple, home-based treatment for childhood myopia—something that currently requires daily eyedrops or specialised contact lenses. The glasses are already sold online for adults, but only children’s growing eyes respond to the treatment, which works by improving blood flow in the choroid layer at the back of the eye. This proof-of-concept study will test four different brightness levels to determine the minimum effective dose, paving the way for a larger, longer trial.
View original technical description
In this project we will begin to find out whether using glasses that shine a red light at the eyes can slow down the worsening of short-sightedness in children. This is important, because short-sightedness now starts at a younger age and worsens faster than in the past. Many people are at risk of permanently losing their eyesight in middle-age because of short-sightedness. Research in China has shown that looking at a low-level red laser light twice daily for 3 minutes can dramatically slow down short-sightedness in children. We do not know whether it would have the same effect on children here, and whether families would use it. We have red-light glasses which are safe to use; adults who wish to maintain good eyesight can buy them over the internet. Red-light treatment improves the blood flow at the back of the eye, in a layer called “choroid”, which can be measured on eye-scans. We have done a study with healthy adults, which showed that red-light is safe and gently improves the blood flow at the back of the eye. In adults, this has no effect on myopia, because their eyes are fully grown. In children, red-light will slow down myopia, and in this project, we want to find out which level of red-light is needed to have this effect. We will ask 24 children age 5-12 years to use red-light glasses for three minutes twice a day for three months. There will be 4 groups of children, and each group will get goggles with a different level of brightness. We will measure the eye length and the thickness of the choroid at the start and 1 and 3 months later and compare the change in eye length between the different groups. In practice, children will need to use the treatment for several years. We will use the results of this study to prepare a longer study with more children.
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