Active Cancer NIHR-supported project Digestion, Kidneys & Other Organs

A phase II study of Zimberelimab anti PD1 immunOtherapy +/- Domvanalimab anti-TIGIT therapy in resectable mismatch repair deficient gastric/gastro-oesophageal junctional AdenoCarinoma (ZODIAC)

About this grant

This summary is based on the grant title only — the full abstract was not available.

No substantive source abstract was published for this research project funded by NIHR.

Researchers

Kai-Keen Shiu (Principal Investigator)

Related Research

Grants with similar aims, by meaning.

ZODIAC: A randomised phase II study of Zimberelimab anti-PD1 immunOtherapy +/- Domvanalimab anti-TIGIT immunotherapy in resectable mismatch repair deficient gastric and gastro-oesophageal junctional AdenoCarcinoma
A Randomized, Open-Label, Multicenter Phase 3 Trial of Domvanalimab, Zimberelimab, and Chemotherapy Versus Nivolumab and Chemotherapy in Participants with Previously-Untreated Locally Advanced Unresectable or Metastatic Gastric, Gastroesophageal Junction, and Esophageal Adenocarcinoma.
A Randomized, Open-Label, Multicenter Phase 3 Trial of Domvanalimab, Zimberelimab, and Chemotherapy Versus Nivolumab and Chemotherapy in Participants with Previously Untreated Locally Advanced Unresectable or Metastatic Gastric, Gastroesophageal Junction, and Esophageal Adenocarcinoma
A Phase 2 Study of Novel Combination Therapies in Participants With Previously Untreated Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma Regardless of PD-L1 Expression Status
VELOCITY-HNSCC Substudy-01: A Phase 2 Study of Novel Combination Therapies in Participants With Previously Untreated Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma Regardless of PD-L1 Expression Status

Original classification

Cancer

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