Unknown Heart, Stroke & Blood NIHR-supported project Pregnancy, Children & Inherited Conditions

Cambridge Blood and Stem Cell Biobank (CBSB)

In plain English

AI plain-English summary

A single biobank in Cambridge will store thousands of blood and stem cell samples donated by patients, making them available for research into blood disorders, stem cell diseases, and normal developmental processes like haematopoiesis. This matters because many research projects collect valuable patient samples but lack the infrastructure to share them beyond the original study team. Without a centralised biobank, those samples often sit unused, limiting the pace of discovery. The Cambridge Blood and Stem Cell Biobank (CBSB) solves that problem by creating a permanent, ethically governed repository. Donors have consented to their anonymised samples and data being used for approved research into the same kinds of conditions they originally agreed to. If the biobank succeeds, it will accelerate research into leukaemia, bone marrow failure, and other blood or stem cell disorders. Researchers outside the original study can apply for access, provided they have ethics approval and comply with the biobank’s access policy. The biobank will publicly report which samples go to which projects, ensuring transparency. This is infrastructure research—it does not itself make discoveries, but it quietly enables the discoveries that improve treatments for patients with blood and stem cell diseases.

View original technical description
The biobank is limited to the purpose for which it was originally compiled, namely for research into blood or stem cell related disorders or study of normal developmental processes, including haematopoiesis. Anonymised samples and/or datasets may be available for ethically approved research of the kind to which the donors originally consented. The samples will firstly be made available to the originator or chief investigator of the study for which the samples were originally obtained. Sub-collections may be closed for a defined period such as the end of the study or trial from which they were originally collected. Only where it is in keeping with the consent given by the patient, or that samples are fully anonymised, or samples collected before September 2006? will samples be made available to researchers outside the original study. Researchers outside the research team will be expected to apply to the biobank for use of the samples or data with ethics already agreed for the proposed study, and to comply with the terms set out in the Access Policy. We will record details of samples exported, the PI and the projects they are going to, and will provide a summary of this in newsletters and on our website.

Researchers

Alan Warren (Principal Investigator)

Related Research

Grants with similar aims, by meaning.

UK Biobank
Volunteers Advancing Medicine Panel: The VAMP Research Tissue Bank (CRF 494)
Exeter Hepatology Collection (non biopsies)
UK Biobank (core renewal)
Genetic Beta Cell Bank Genetic Beta Cell Research Bank

Plain English summaries and category classifications on this site are generated by AI and may not perfectly reflect the original research.