One in three older patients admitted to NHS hospital wards develops delirium—acute confusion that lengthens stays, raises mortality risk, and often leads to nursing home placement. This project adapts a proven North American prevention system, the Hospital Elder Life Program (HELP), for use in UK acute trusts. HELP trains hospital staff and volunteers to deliver a standardised package of interventions—such as orienting patients, promoting sleep, and ensuring adequate hydration—that has cut delirium rates by about one third in US hospitals. The research team will first review and adapt HELP through case studies in three hospitals, then test its feasibility and acceptability in at least three more, and finally run a cluster-randomised feasibility trial across six centres to gather preliminary data on effectiveness and cost-effectiveness. If HELP proves implementable in the NHS, it could become a routine, scalable system for preventing a common and costly complication of hospitalisation, reducing harm to older patients and easing pressure on hospital beds and care homes.
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AIMS AND OBJECTIVESAim:To improve delirium prevention for older people admitted to NHS acute hospitals through a programme of linked projects to investigate the feasibility, acceptability, potential effectiveness and cost-effectiveness of a delirium prevention system of care.Objectives:1. Review and adapt the Hospital Elder Life Program (HELP) for use in the UK. HELP is an existing, standardised and manualised North American multi-component system of care that has been demonstrated to prevent the development of delirium in hospitalised older patients in the USA. It is delivered by specially trained hospital staff and volunteers.2. Identify strategies to support the implementation of HELP. 3. Determine the optimum methods to deliver HELP in routine care.4. Conduct a feasibility study to assess the implementation and acceptability of HELP, refine the content and delivery of HELP, determine preliminary estimates of effectiveness and cost-effectiveness, assess feasibility of conducting a definitive trial and gather data to inform its design. BACKGROUNDDelirium (also called acute or toxic confusion) is the most frequent complication following hospitalisation for older people. Evidence suggests it could be prevented in about one third of patients using multi-component interventions but these are not yet routinely available in the NHS.IMPORTANCEThe issue of delirium has been recognised as a priority area (NSF for Older People). Delirium occurs in about a third of patients admitted to medical wards and is associated with longer lengths of stay, increased mortality, incomplete functional recovery and increased need for institutional care.NEED FOR RESEARCHThere is no generalisable system of care in the UK capable of reliably preventing delirium. PAST AND CURRENT RESEARCHThere has been only limited international research but multi-component prevention interventions have been associated with a reduction in delirium of about one third.WORK UNDERTAKENWe have presented HELP to local hospital voluntary services managers and have conducted workshops with local voluntary services and nurse managers, ward staff, hospital volunteers and our consumer group. The proposed new roles for staff and volunteers have been positively received.RESEARCH PLANSProject 1: Review and adapt HELP for use in the UKUsing case studies in three general hospitals, we will review and adapt HELP and identify potential implementation and delivery strategies. Each case study will comprise a HELP development team and staff from an orthopaedic or elderly care ward.Project 2: Pilot to test implementation feasibility and acceptability of HELPWe will use further case studies in at least three different hospitals to investigate feasibility and acceptability of HELP to provide a realistic assessment of the practical, professional and cultural issues associated with HELP implementation. Project 3: Preliminary testing of the HELP delirium prevention system of careWe propose to conduct a cluster randomised, controlled, feasibility study in six centres to test for preliminary evidence of effectiveness and cost-effectiveness and to gather data to inform recruitment, appropriate outcome measure selection and sample size to design a large scale trial. RESEARCH TEAMOur research team includes national and international leaders in delirium (including the chair and members of the NICE Clinical Guideline Development Group for delirium) and elderly care research and experts in the development and evaluation of complex interventions, research to improve nursing practice, health economics, statistics, clinical trials, quantitative and qualitative research methods, workforce planning, NHS management. RESEARCH ENVIRONMENTThe Academic Unit of Elderly Care & Rehabilitation, University of Leeds, is based in Bradford and has a record of more than 15 years of health services research using multi-method research designs including randomised control trials, systematic reviews and qualitative and health
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