Completed Pregnancy, Children & Inherited Conditions Psychology & Behaviour

Social, emotional & biological processes in emergent conduct disorders: Wirral Child Health & Development Study 1-4 yrs

In plain English

AI plain-English summary

A baby’s angry outbursts or emotional flatness at four weeks old may predict whether they become a violent teenager. Researchers are following 1,286 first-time mothers and their children from pregnancy to age four, tracking genetics, stress during pregnancy, parenting behaviour, and the child’s own physiology and emotional responses. The goal is to untangle why some children develop serious aggression while others do not. Behaviour problems that start early and become entrenched are hard to reverse. They often lead to violence, mental health difficulties, and trouble parenting the next generation. Current parenting support works for some families but not all, partly because children become aggressive for different reasons—some are easily triggered into anger, others become emotionally numb. Without knowing which child is on which path, interventions remain blunt. If this study succeeds, it will map distinct developmental routes to aggression, each with its own biological and social signature. That would allow clinicians to match specific families to targeted support before problems harden. The research is fundamental science—it is not testing an intervention yet—but understanding the underlying pathways is the necessary first step toward preventing chronic violence rather than just managing it.

View original technical description
This study aims to find out why some children develop behaviour problems from an early age and what factors lead to them persisting. If these difficulties are not understood and families are not helped by informed therapeutic interventions, these problems commonly develop into serious aggression or violence during adolescence and adulthood. These young people develop additional mental health and relationship problems and may then have marked difficulties parenting their own children safely. If identified early, some childhood behaviour can be helped by supporting parents in using optimal parenting strategies. However, once problematic behaviour has become entrenched it can become harder to change. We need to be able identify and understand these vulnerable children early in their lives, so chronic problems can be prevented. Children become aggressive for different reasons and we need to know more about these. Some infants may be temperamentally more easily triggered into angry outbursts, and may become angrier in response to experiencing angry behaviour towards them or around them. Other babies may be born less emotional than average, and become less emotionally responsive to the feelings of other people as they grow up. Other children, able to feel emotions when very young, may find ways of dampening down their emotions if they are frightened over time and do not experience parental comfort. Thus different ways of responding emotionally during early life may lead to later aggression. Many factors including the genetic make-up of the child, stress during pregnancy or in early life, and parents? availability or ability to respond to their baby?s emotions probably affect how they develop. We are currently following1286 first time mothers, partners and babies during pregnancy until the babies? first birthdays. Many infants will develop without behavioural difficulties and it is important to study them too. A sub-group of 300 mothers reporting differing levels of stress have agreed to tell us about their lives in more detail, and let us observe their children?s emotions, mother-child relationships, their child?s physiology and problem solving at 4 weeks, and 6 and 12 months of age. We aim now to follow the parents and children up to 4 years of age by which time some families will have given us detailed information at 10 time points in their lives. The study design, quality and frequency of assessments will enormously improve our understanding of the developmental pathways to aggression, improving chances of developing targeted interventions.

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Researchers

Andrew Pickles (Co-Investigator)Helen Sharp (Co-Investigator)John Quinn (Co-Investigator)Jonathan Hill (Principal Investigator)Vivette Glover (Co-Investigator)

Related Research

Grants with similar aims, by meaning.

Prenatal and infancy origins of biological and social-cognitive processes in disruptive behaviour problems in children aged 7 - 9 years.
Early Prediction of Violence and the Disruptive Behaviour Disorders: Follow-up of the Cardiff Child Development Study
The Wirral Child Health and Development Study
Conduct Problems in children: Refining the neurocognitive phenotype
How early stress gets under the skin: The role of DNA methylation in the development of youth conduct problems and comorbid symptoms

Original classification

Research Grant

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