Active Lungs & Breathing Infection & Immunity

Inflammation and Immunity

In plain English

AI plain-English summary

A new research programme will build detailed maps of how people with common allergic and breathing conditions are treated across the UK, linking their care to their health outcomes. This matters because care for conditions like asthma and hay fever varies widely depending on where someone lives, and the reasons for that variation are poorly understood. Without systematic data, healthcare services cannot identify which practices work best or where inequalities are worst. The programme will create tools that allow researchers and clinicians to spot these gaps and target improvements. If successful, the maps and analytical tools could help the NHS reduce unwarranted variation in treatment, improve outcomes for millions of people with breathing problems, and cut costs from ineffective care. The programme also aims to build a reusable infrastructure—methods and data platforms—that other researchers can apply to different respiratory conditions, enabling better prediction, prevention, and management of illness across the board. This is primarily a translational and data-science effort, not fundamental science; its value lies in making existing knowledge actionable at scale.

View original technical description
The Inflammation and Immunity research programme will transform the UK capabilities to understand the inner workings of disease. The research will develop ways to map the people suffering from common allergic and breathing conditions alongside information on their care and outcomes across the UK. The maps will be used to explore variation in how people are cared for and develop tools to help healthcare services improve and reduce inequalities. This will lay the foundations, building tools and new ways, for other researchers to understand and improve care for other causes of breathing conditions, and develop ways to better predict, prevent and manage illness.

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Researchers

Jennifer Quint (Principal Investigator)

Related Research

Grants with similar aims, by meaning.

InSIGHT: Integrating Statistical methods, Immunology and Genomics for Healthcare Translation
University of Edinburgh/MRC Centre for Inflammation Research
Cellular dynamics in chronic lung disease: the neglected B cell axis
The crosstalks between immune cells, bacteria and epithelial cells in the intestine: elucidating their cellular and molecular mechanisms
INITIALISE: Inflammation in human early life: targeting impacts on life-course health

Original classification

Intramural

Plain English summaries and category classifications on this site are generated by AI and may not perfectly reflect the original research.