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Soft Robotic Total Larynx Replacement

In plain English

AI plain-English summary

A single soft robotic device aims to replace the entire larynx, using flexible materials and muscle signals to let patients breathe, speak, and swallow without choking. Current total laryngectomy removes the voice box entirely, leaving patients with a permanent tracheostomy and no natural way to speak or protect their airway from food and liquid. Existing mechanical replacements rely on rigid, multi-component designs that fail to mimic the larynx’s complex musculature and increase infection risk. This project addresses that gap by exploiting soft robotics—flexible, elastic materials that can morph into compliant shapes—to build a monolithic synthetic larynx. The device is controlled by electromyography, reading electrical signals from preserved neck and mouth muscles to infer when the user is speaking or swallowing. If successful, the implant would restore three core larynx functions—aspiration prevention, respiration, and phonation—in a single biocompatible unit, with a failsafe mode. This could transform life for laryngectomy patients, eliminating the need for external voice prosthetics or permanent stoma care. The research is applied and device-focused, with immediate clinical relevance rather than fundamental science.

View original technical description
The technology to be developed combines novel soft robotics with proven biocompatible materials and electromyography to produce a synthetic total larynx replacement. T radWonal robotic approaches that utilise rigid material are not sufted for long term integration in the larynx due to insufficient replication of the natural musculature and physiology and the requirement for multi-component designs that increase infection risks. By exploiting advances in soft robotics, which utilises flexible and elastic intelligent materials to morph compliant structures into complex shapes, we bypass the difficultiesencountered with traditional, hard, robotics. This enables the manufacture of a monolithic synthetic larynx, made biocompatible through combination with a clinically proven airway implantable synthetic polymer. The device is controlled by electromyography of the strap muscles and muscles of the floor of the mouth, which can be preserved in laryngectomy, to infer when the patient is speaking or swallowing. The implanted device will robustly replicate the core functionality of the larynx (aspiration prevention, respiration and phonation) with a failsafe modality.

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Researchers

Martin Birchall (EPMC Awardee)

Related Research

Grants with similar aims, by meaning.

RegenVOX. Stem-cell based, tissue engineered laryngeal replacement.
Tissue-Responsive Robotic Implants for In Vivo Mechanostimulation-Based Tissue Regeneration (Tissue-RIMOTE)
Self-Motile Implantables for Advanced Neural Interfaces
Digital Speech Recovery from Articulator Movement (DiSArM)
Intratracheal Valve device for intractable aspiration: ITV

Original classification

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