Completed Public Health & Healthcare Infection & Immunity

Supporting the WHO R&D Blueprint to prevent epidemics 2018-2019

In plain English

AI plain-English summary

The World Health Organization is coordinating a global playbook to ensure that when the next epidemic hits, diagnostics, drugs, and vaccines are ready to deploy within weeks, not years. This matters because outbreaks such as SARS, Ebola, and Zika have shown that the world is dangerously unprepared. In an increasingly connected and urbanising world, a pathogen that emerges in one city can reach every continent in hours. The economic and human costs of these failures are enormous, yet no single country or company can solve the problem alone. The WHO’s R&D Blueprint, established in 2015, exists to close that gap by creating a global strategy for rapid research and development during health emergencies. If this work succeeds, the systems that quietly protect public health will become faster and more reliable. The Blueprint coordinates national governments, funders, drug companies, and regulators to streamline how data and samples are shared, how ethical and regulatory pathways are cleared, and how vaccines and treatments are tested and approved during a crisis. The result is not a single product but a permanent infrastructure—a set of norms, standards, and relationships that can be activated the moment a new threat appears, saving lives and averting large-scale crises before they spiral out of control.

View original technical description
In an increasingly connected and urbanizing world, disease outbreaks are a growing risk to people’s lives and livelihoods. As illustrated by recent pandemics, such as SARS, Ebola and Zika virus, they also have significant impact on economies and challenge health infrastructures. They require coordination and increased efforts at the national, regional and global level to ensure we’re better prepared for future outbreaks. Addressing epidemics and other health emergencies is one of the WHO’s three core priorities in its new General Programme of Work (2019-2023). In 2015, WHO established the R&D Blueprint, which outlined a global strategy and plan to allow the rapid activation of R&D activities during epidemics. A large focus is to coordinate global efforts in developing effective diagnostics, medicines and vaccines for outbreaks to save lives and avert large scale crises. The Blueprint works with national governments, UN agencies, civil society, funders and the private sector to improve coordination, accelerate processes and develop tailored norms and standards. This project would allow key areas of work to move forward: (1) coordination, (2) data and sample sharing and related ethics, (3) outlining appropriate regulatory and ethical pathways and implementation of IVTF recommendations, and (4) data sharing for public health emergencies.

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Researchers

Erin Kenney (EPMC Awardee)

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Original classification

Discretionary Award - Policy

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