Completed Engineering Cancer

University of Cambridge Translational Partnership Award

In plain English

AI plain-English summary

The University of Cambridge is building a virtual "Therapeutic Hub" to turn its fundamental biological discoveries into real treatments for patients. This matters because a vast gap exists between laboratory breakthroughs and clinical applications. Many promising discoveries never reach patients because academics lack the specialised knowledge, industry connections, or funding needed for early-stage drug development. The hub will provide training, expert advice on regulatory and commercial pathways, and access to contract research organisations—bridging the gap between discovery science and clinical translation. If successful, the hub could transform how Cambridge researchers move projects from bench to bedside. It will cover drug discovery, cell and gene therapy, regenerative medicine, diagnostics, and medical devices. The goal is to push more projects toward clinical testing. The hub also includes women-focused networking events and self-taught training packages, aiming to create lasting cultural change in how the university approaches translation. The ultimate impact would be a steady pipeline of new treatments emerging from Cambridge's fundamental science, rather than promising discoveries languishing in academic journals.

View original technical description
We aim to encourage and support scientists to realise the translational potential of their basic research. By the creation of a virtual Therapeutic Hub, which provides an integrated facility for training, advice, collaboration, funding and contracted services, we will establish a bridge between discovery science and early stage translation. The Therapeutic Hub will provide opportunities for academics across Schools to carry out target validation by functional genomics approaches, as well as working with drug discovery experts including CROs and Experts in Residence. Access to consultancy services will provide bespoke advice, such as regulatory or health economics, to support successful applications and commercialisation. The hub will cover projects spanning drug discovery, drug repurposing, cell and gene therapy, regenerative medicine, diagnostics, medical deices, apps, biomarkers and imaging. The focus will be to progress projects towards the clinic. In addition to research facilitation, regular events will take place, including women focused networking events and self-taught virtual training packages will be created. Overall the activities proposed will fill the critical gap in the Cambridge translational pipeline and create a legacy of Departmental Translation Champions delivering sustained behavioural change in the biomedical translational landscape at the University of Cambridge.

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Researchers

Andy Neely (EPMC Awardee)

Related Research

Grants with similar aims, by meaning.

Institutional Translation Partnership Award (iTP A): University of Cambridge
UCL/WT Translational Partnership 2018 - Widening Participation and Enhancing Translational Culture
University of Leeds Translational Partnership Award
Newcastle Wellcome Trust Translational Partnership
Innovations Translational Partnership Award (Manchester)

Original classification

Innovations Translational Partnership Award

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