Completed Infection & Immunity Heart, Stroke & Blood

Implementation of the Influenza Vaccines Roadmap – Proposal for Monitoring, Evaluation and Adjustment

In plain English

AI plain-English summary

A global roadmap for developing better flu vaccines is about to get a three-year progress check and update. The Influenza Vaccines R&D Roadmap, completed in 2021 after extensive global consultations, laid out a strategy to accelerate development of improved seasonal flu shots and broadly protective or universal vaccines. But a roadmap only works if someone tracks whether anyone is following it. This project will monitor progress against the roadmap’s milestones, identify where knowledge gaps or barriers remain, and revise the strategy based on what has—or has not—happened. It will also incorporate lessons from the rapid development of COVID-19 vaccines, which may offer shortcuts for flu vaccine innovation. If successful, this monitoring and adjustment process will keep the global research community coordinated and accountable. Rather than each lab or company working in isolation, the updated roadmap and its website will serve as a shared reference point, helping funders and researchers spot bottlenecks and redirect resources. The result could be faster development of flu vaccines that work better and last longer, reducing the annual burden of seasonal influenza and strengthening preparedness against a future flu pandemic.

View original technical description
Improved influenza vaccines are urgently needed to reduce the global burden of seasonal influenza and enable an effective public health response to the ongoing pandemic threat from emerging influenza viruses. The Influenza Vaccines R&D Roadmap (IVR), completed in September 2021 following an extensive global stakeholder engagement process, provides a framework for guiding R&D activities aimed at accelerating the development of improved seasonal influenza vaccines and broadly protective or universal influenza vaccines. To ensure successful implementation of the roadmap’s strategies, follow-up activities are needed to promote awareness, encourage stakeholder buy-in, and track outcomes. CIDRAP proposes to conduct a 3-year project to: (1) monitor and evaluate progress in achieving the IVR goals and milestones, including changes in the status of knowledge gaps and barriers to influenza vaccine R&D; (2) revise and update the roadmap to reflect R&D progress, changes in timelines, new knowledge gaps and barriers to influenza vaccine R&D, and learnings from the ongoing development of COVID-19 vaccines; and (3) maintain and update the IVR website as a communications hub for the influenza vaccine R&D community to strengthen engagement and share information and new developments.

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Researchers

Kristine Moore (EPMC Awardee)Michael Osterholm (EPMC Awardee)

Related Research

Grants with similar aims, by meaning.

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Original classification

Discretionary Award - Vaccines

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