Active Mental Health Psychology & Behaviour

Madness in Medicine: Psychotic experiences and innovative approaches to mental health care in the UK

In plain English

AI plain-English summary

Psychedelic therapy trials exclude people with a history of psychosis, even though the drugs themselves can trigger psychotic-like experiences. This project investigates that contradiction. The researcher will embed in NHS clinics—both conventional psychosis wards and experimental psychedelic therapy settings—to observe how clinicians and patients define a “safe” or “therapeutic” psychotic experience in each context. The problem is that two rapidly evolving fields are talking past each other: psychedelic research treats psychotic experiences as potentially healing, while mainstream psychiatry treats them as dangerous and stigmatising. This gap leaves a highly disadvantaged group—people with psychosis, who are disproportionately from racialised and low-income communities—excluded from innovative treatments. If the research succeeds, it could reshape how mental health policy defines safety and efficacy. It may help destigmatise psychotic experiences and inform more equitable trial designs that do not automatically exclude people with psychosis. This is fundamental social science: it will not produce a new drug or device, but it could change the assumptions that underpin how such treatments are developed and who gets access to them.

View original technical description
This community-engaged clinical ethnography investigates psychotic experiences and mental health care within the UK’s National Health Service. Experimental psychedelic-assisted therapy mobilizes psychotic experiences as therapeutic in clinical trials. Yet these trials exclude people with a history of psychosis, a highly stigmatised condition that disproportionately impacts racialised and disadvantaged communities. At the same time, conventional psychosis treatments—antipsychotic drugs—are increasingly recognised as insufficient, and cutting-edge psychosis clinics are foregrounding new approaches to managing psychotic illnesses. This project bridges divided research on psychedelics and psychosis to investigate psychotic experiences across these disparate clinical contexts and discover how innovative treatment approaches that mobilize or manage psychotic experiences are transforming mental health care. Through clinical ethnography, participatory arts-based research, and collaborative codesign with patients and clinicians, this research will provide insight on how therapeutic value, safety, and efficacy are changing in the context of the burgeoning ‘psychedelic renaissance’ and global mental health crisis. This project will advance scholarly debates in anthropology and science and technology studies, with implications for destigmatising ‘madness’ and developing more equitable mental health care policy and practice.

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Researchers

Meredith Evans (EPMC Awardee)

Related Research

Grants with similar aims, by meaning.

Changing minds: mapping out the bioethical dimensions of psychedelic-assisted psychotherapy
'Psychedelic Selves': Neoliberalism, Neuroscience, and the British Psychedelic Renaissance
Reconstructing the Social Link: A Clinical Anthropology of the Psychoanalytic Treatment of Psychosis
Investigating the potential of psychedelic-enhanced cognitive interventions for young people with self-harm behaviour: mechanisms, acceptability....
A Philosophical Phenomenology of Psychedelic Therapy

Original classification

Early-Career Award

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