Associated organisationsKEMRI-Wellcome Trust Research Programme · Kenya Paediatric Research Consortium · London School of Hygiene & Tropical Medicine · University of Georgia · University of Nairobi · University of OxfordEurope PMC affiliations are not treated as award recipients or mapped locations.
Funding£2.7M
PeriodOct 2025 — Oct 2028
In plain English
AI plain-English summary
Aflatoxins—fungal poisons that contaminate maize and peanuts—are silently damaging children’s immune systems across Africa, and climate change is making the problem worse. The TRACE project tackles a blind spot in global health policy. Although aflatoxin exposure is linked to malnutrition and weakened immunity in children, direct evidence of its role in driving infections is scarce. Climate change is expected to increase contamination, yet aflatoxins are absent from most climate and child health agendas. The team will connect two decades of climate data to aflatoxin exposure trends, generating the first large-scale empirical evidence of this link. If successful, the research could reshape how governments and international agencies approach food safety and child health in a warming climate. The team will test a community-designed intervention in Kenya and The Gambia, measuring its effects on aflatoxin exposure, febrile illness, and vaccine responses. They will also model future health and economic risks under different climate scenarios. The goal is to embed mitigation measures into national policies and local farming practices, protecting millions of children from a largely invisible but growing threat.
View original technical description
Our proposal, TRACE, addresses a neglected challenge affecting millions of households in Africa at the intersection of climate change, food safety, and child health. Aflatoxins, toxins produced by fungi in staple crops such as maize and peanuts, pose a growing threat as climate change creates conditions that favour contamination. Exposure has been linked to impaired immunity and malnutrition in children, heightening vulnerability to infections. However, direct evidence remains limited, and aflatoxins are largely absent from climate and child health policy agendas, hindering implementation of mitigation measures.Within the first year of the award, we will connect two decades of climate data to aflatoxin exposure trends, generating the first large-scale empirical evidence of the climate-aflatoxin-child health link. We will then test an intervention package co-designed with communities in Kenya and The Gambia, measuring effects on aflatoxin exposure, acute febrile illness, and vaccine immune responses among children. We will model future health and economic risks under climate change scenarios to inform long-term solutions.Our transdisciplinary team integrates expertise in epidemiology, climate science, immunology, anthropology, food science, and policy engagement. Strong partnerships with communities, governments, and international agencies will ensure findings are rapidly and sustainably embedded into policy and local farming practices.
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