Completed Infection & Immunity Public Health & Healthcare

Supporting WHO's work in epidemic preparedness

In plain English

AI plain-English summary

The World Health Organization is rolling out a dozen distinct initiatives to strengthen how the world detects and responds to infectious disease outbreaks. This matters because epidemic preparedness remains patchy: many countries lack the tools to assess their own vulnerability, response protocols for diseases like Ebola and Marburg are not standardised, and genomic surveillance data often sits disconnected from outbreak tracking systems. The project tackles these gaps directly, from designing software that links pathogen genetic sequences with real-time surveillance, to pre-positioning vaccines and running clinical trial training in target countries. If the work succeeds, national health agencies will have practical, field-tested tools to spot outbreaks earlier and mount faster, more coordinated responses. The rodent control strategy, for example, targets a common but overlooked route of disease spillover. The research roadmaps for Rift Valley fever, Zika, and meningitis will give funders and scientists clear priorities for diagnostics, vaccines, and treatments. These are infrastructure improvements—quiet, unglamorous, but essential for preventing local outbreaks from becoming global crises.

View original technical description
This project includes twelve diverse areas of work conducted by WHO to increase epidemic preparedness, including the development of an Innovative Rodent Control and Human Health strategy; development of a tool to assess epidemic vulnerability of countries; a scoping plan for design software to link genomic and surveillance data; the use of modern sequencing technologies in outbreak response; defining Standard of Care (SoC) for Ebola and Marburg outbreaks; support to the Zika virus(ZIKV) Individual Participant Data (IPD) Consortium; development of new modules for GO-Data and improved functionality and rollout of training of super-users; gene editing technologies and implications for human health; development of generic protocols prepositioning and training for Ebola vaccines deployment and Ebola therapeutics clinical trials in target countries; development of a Rift Valley Fever (RVF) R&D Roadmap; development of a Zika R&D Roadmap through holding the first Taskforce meeting; and first steps in developing a Meningitis R&D Roadmap. The total cost is 2,510,000 USD The costs are 2,183,700 USD plus 326,300 USD programme support costs (13%).

View the original record at the funder ↗

Researchers

Erin Kenney (EPMC Awardee)

Related Research

Grants with similar aims, by meaning.

Supporting the WHO R&D Blueprint to prevent epidemics 2018-2019
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Virus Genomics for Outbreak Response (ViGOR) in Central/East Africa
Improving early warning and control of mosquito-borne disease outbreaks caused by extreme weather in Uganda
MRC Centre for Global Infectious Disease Analysis (MRC GIDA)

Original classification

DFID-Wellcome Epidemic Preparedness Grant

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