Completed Cancer Infection & Immunity

RECOVERY (Randomised Evaluation of COVID-19 Therapy) International

In plain English

AI plain-English summary

The RECOVERY trial is expanding from the UK into hospitals in Indonesia, Nepal, and Vietnam, with plans to open sites in Africa. The trial has already recruited over 13,500 patients and produced three world practice-changing results within its first 100 days. Now, clinical investigators from low- and middle-income countries (LMICs) want to join. This matters because the pandemic will continue at different paces across the globe for at least another 24 months. Without international coordination, smaller, uninformative studies waste resources and delay answers. Expanding RECOVERY lets researchers test new treatments faster, in populations where the disease behaves differently, and where healthcare systems are often under greater strain. If successful, the trial will generate results that are globally relevant, not just applicable to wealthy countries. It will also build clinical research capacity in LMICs, enabling those countries to run their own high-quality studies in future pandemics. For patients in these regions, the payoff is access to proven treatments sooner, rather than relying on evidence generated elsewhere that may not apply to them.

View original technical description
The Phase 3 RECOVERY platform has been a success, recruiting over 13,500 patients and producing 3 clear, world practice-changing results in the first 100 days of recruitment. The RECOVERY team has been approached by clinical investigators from various LMICs who wish to participate in RECOVERY. As it becomes clear that this pandemic will continue at various locations and paces over the next 24 months, there is an opportunity to increase the impact of the RECOVERY trial by expanding internationally. Expansion has the potential to speed up the assessment of novel treatments, increase the global relevance of the trial results, build capacity, and reduce wasted efforts on small uninformative studies. The key goal is to establish RECOVERY internationally, initially in Indonesia, Nepal and Vietnam, with a view to opening sites also in Africa.

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Researchers

Buddha Basnyat (EPMC Awardee)Guy Thwaites (EPMC Awardee)Peter Horby (EPMC Awardee)Raph Hamers (EPMC Awardee)

Related Research

Grants with similar aims, by meaning.

Randomised Evaluation of Covid-19 Therapy [RECOVERY]
Randomised Evaluation of COVID-19 Therapy (RECOVERY)
RECOVERY - Randomised Evaluation of COVID-19 Therapy
20IA10 - Randomised Evaluation of COVID-19 Therapy (RECOVERY)
Randomised Evaluation of Covid-19 Therapy [RECOVERY].

Original classification

Research Grant

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