Active Public Health & Healthcare Infection & Immunity

Global.health: data science and sharing for early response to emerging infectious diseases

In plain English

AI plain-English summary

When a new infectious disease emerges, Global.health will pull together clinical records, genetic sequences, and epidemiological data from around the world in near real-time and feed them into predictive models. The problem is that outbreak response today is fragmented. Data sits in separate silos—hospitals, labs, government agencies—and arrives too late or in incompatible formats. This delays decisions about where to deploy vaccines, impose travel restrictions, or allocate hospital beds. Low- and middle-income countries, where outbreaks often hit hardest, also lack the data science capacity to analyse what they collect. If this platform works, it will change how international bodies like the World Health Organization coordinate early responses. The same pipelines and open-source tools could also track climate-driven disease outbreaks—for example, predicting where rising temperatures will push mosquito-borne illnesses next. Beyond infectious diseases, the privacy-preserving analytics tools developed here could apply to any sensitive data, from census records to patient registries, improving how governments and researchers share information without compromising individual privacy.

View original technical description
Infectious diseases pose a grave threat to humanity due to factors such as increased travel, deforestation, and population growth. To address this challenge, Global.health aims to enhance the response to infectious diseases by creating an integrated platform that provides real-time access to clinical, epidemiological, genomic, and contextual data. This platform will train predictive models to effectively respond to current and future disease threats and promote equitable partnerships to improve data sharing and strengthen data science capacity in low- and middle-income countries. The project has four main goals: 1) developing rapid data dissemination pipelines and integrating them with the World Health Organization (WHO) for early international coordination and response; 2) building data integration pipelines and predictive models for climate-driven disease outbreaks in vulnerable regions; 3) developing tools to detect and correct biases in infectious disease data, improve data quality, and enable privacy-preserving distributed analytics; and 4) increasing adoption of Global.health's technology stack by engaging with WHO teams, regional offices, member states, partner organizations, and the research community. By achieving these aims, Global.health will significantly enhance the infectious disease data ecosystem, assess the value of integrating different data types during outbreaks, and create adaptable open-source tools applicable beyond infectious diseases.

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Researchers

Aalisha Sahukhan (EPMC Awardee)John Brownstein (EPMC Awardee)Oliver Morgan (EPMC Awardee)Samuel Scarpino (EPMC Awardee)

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Original classification

Discretionary Award

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