Active Lungs & Breathing NIHR-supported project Pregnancy, Children & Inherited Conditions

RAPID Supported Rescue packs post-discharge in chronic obstructive pulmonary disease: An open-label multicentre randomised controlled trial

In plain English

AI plain-English summary

Every year, thousands of people with COPD are discharged from hospital after a severe flare-up, only to be readmitted within 90 days. This trial tests whether giving them a “rescue pack” of antibiotics and steroids—along with clear instructions and twice-weekly phone or text support—can cut that rate of return. The problem is straightforward: the period immediately after a COPD exacerbation is dangerously unstable. Patients often deteriorate at home, unsure when to seek help or start medication. Current practice leaves them to manage this alone, and hospital readmissions are common, costly, and distressing. If the rescue pack strategy works, it could change how the NHS manages post-discharge care for COPD. Instead of a passive handover, patients would have a concrete action plan and regular check-ins. This could reduce pressure on hospital beds, lower healthcare costs, and give patients more confidence to manage their own condition at home. The trial is an open-label, multicentre randomised controlled trial—a practical test of a simple intervention that, if effective, could be rolled out widely without major new infrastructure.

View original technical description
To test the hypothesis that provision of a rescue pack of antibiotics and corticosteroids, together with written (and translated) education on their use and twice-weekly telephone (or text) based support for when to use rescue packs, can reduce all-cause hospital re-admission in the 90-day high-risk period following discharge from hospital after an exacerbation of COPD

Researchers

Charlotte Bolton (Principal Investigator)

Related Research

Grants with similar aims, by meaning.

Rescue packs post-discharge in chronic obstructive pulmonary disease: An open-label multicenter randomisedcontrolled trial (RAPID)
Rescue packs post-discharge in chronic obstructive pulmonary disease: An open-label multicenter randomisedcontrolled trial
Rescue packs post-discharge in chronic obstructive pulmonary disease (The RAPID study)
Optimised Inhalers to Reduce COPD Exacerbation Re-Admissions and Mortality - a Feasibility Study
Improving safety and TReatment precision for Acute COPD Exacerbations: Feasibility trial of a primary care assessment pathway using point-of-care testing (TRACE).

Original classification

Respiratory Medicine

Plain English summaries and category classifications on this site are generated by AI and may not perfectly reflect the original research.