University of Newcastle Centre for Brain Ageing & Vitality supported by BBSRC, EPSRC, ESRC and MRC
In plain English
AI plain-English summaryAs the UK population lives longer, the new MRC Centre for Brain Ageing and Vitality in Newcastle will investigate why the brain ages and how exercise and diet can keep it healthy. This matters because old age is often linked to poor health, and the greatest risk factor for dementia and Parkinson’s disease is simply being elderly. Researchers still do not understand why the ageing brain becomes vulnerable to these diseases, or how lifestyle choices might slow that process. If the centre succeeds, it could produce clear, evidence-based guidance on how much exercise people need to stay mobile and which dietary ingredients are most protective as they age. This would give older adults and their doctors practical tools to maintain brain and body function longer, potentially delaying or reducing the burden of age-related diseases. The research is a mix of fundamental science—understanding the basic biology of brain ageing—and applied questions about real-world interventions. Past discoveries in fundamental ageing biology have already led to insights into metabolism and inflammation; this centre aims to build on that foundation to improve health in later life.
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