Completed Pregnancy, Children & Inherited Conditions Food & Agriculture

GCRF Action against Stunting Hub

In plain English

AI plain-English summary

A child’s growth is not just a matter of food—it is shaped by a cascade of biological, social, and environmental factors that scientists have studied in isolation for decades. This project aims to break down those silos by treating child stunting as a whole-body, whole-community problem rather than searching for a single cause or cure. The researchers will work in over 50 communities across India, Indonesia, and Senegal, tracking how infections, gut microbes, diet, hygiene, and even epigenetic changes interact to derail a child’s growth. They want to identify the tipping points where healthy development stalls, and then test child-centred interventions that disrupt that cascade. If successful, the project could reduce stunting by up to 10% in those communities and build a decision-making platform that governments and aid agencies can use to predict which interventions will work before spending money. The ultimate ambition is to improve the lives of up to 1 million children—not by offering a single fix, but by understanding the whole mosaic of factors that keep children small.

View original technical description
The global community aims to decrease the number of stunted children under five by 40% by 2025. While targeted and specific, we know that this is presently unachievable. Part of the problem is that over the last three decades, the search for the 'silver bullet' or the specific driver, which if addressed could solve this intractable problem, has narrowed praxis. This is not to say that gains have not been made, but rather our efforts have not been entirely impactful. While substantial disciplinary advances have occurred, often they have not been joined-up. And while systematic reviews abound, pan-disciplinary understandings, do not. Hence, child stunting is an intractable problem, waiting for a unified solution. If we perceive child under-nutrition as a mosaic, we have knowledge of many of the individual elements. For example, biological advances demonstrate there is an identifiable 'epigenetic signature' of stunting. Children who are stunted also have immature gut micro-biomes and we also know a large proportion of the global malnutrition burden is caused (either directly or indirectly), by infectious agents ranging from viruses and bacteria to protozoa and helminths. Food-borne toxins also impact stunting. Equally, we know a range of elements can help to prevent stunting from animal source Foods (ASF) to behavioural elements from dietary choices to feeding practices to water, sanitation and hygiene (WASH). Yet overall, it may be argued that we are missing the shape and structure of the mosaic and the synergies between the component parts. In many quarters, the literature on child under-nutrition is viewed as 'siloed' and non-relational (Perkins et al., 2017). But equally importantly, 'integrated' nutritional programmes have often not had the expected impacts. Herein lies the problem and the related solution: we urgently need to understand the 'cascade' of factors driving child stunting and the synergies and inter-relationship between drivers. And equally importantly, we need to better understand the 'tipping points' or the critical points along this cascade where healthy linear growth diverges to slow or no growth. To do this, we propose to transform our exploration of child under-nutrition from the component parts to the 'whole child'. Where the biological, social, environmental and behavioural context in which stunting occurs is understood in its entirety and where the strength and directionality of these drivers, inform related interventions. Based on this joined-up approach, we will explore the ability of a range of child-centred interventions to disrupt the cascade of factors that inhibit the ability of a child to grow. These actions and outcomes will then form the basis of a decision-making platform to enable users to identify the ex-ante and ex-post impacts of potential interventions. Embedded in this process, however, is a values-based approach that ensures that from the outset, our research directly connects to and betters the lives of the children, families and communities involved. We will work across three countries: India, Indonesia and Senegal in over 50 communities. We aim to decrease child stunting by up to 10% our communities. Finally, to enhance our impact and legacy our Hub, we will engage a range of end-users in both our outputs and in the wider 'whole child' approach. We will support new regional platforms on maternal and child nutrition proposed by UNICEF linking the work of FAO/The World Bank/WHO at the country-level. We will also engage our network of over 100 civil society organizations in our findings. Over the course of the project, we expect to positively impact the lives of up to 1 million children.

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Researchers

Alan Walker (Co-Investigator)Babacar Faye (Co-Investigator)Bharati Kulkarni (Co-Investigator)Bhavani Shankar (Co-Investigator)Claire Heffernan (Principal Investigator)Delia Grace (Co-Investigator)Elaine Ferguson (Co-Investigator)Joanne Webster (Co-Investigator)Julie Dockrell (Co-Investigator)Lynn Ang (Co-Investigator)Marie K Harder (Co-Investigator)Paul Haggarty (Co-Investigator)Peter Wood (Co-Investigator)Stephen Allen (Co-Investigator)Suneetha Kadiyala (Co-Investigator)Todd Rosenstock (Co-Investigator)Umi Fahmida (Co-Investigator)Valerie Curtis (Co-Investigator)

Related Research

Grants with similar aims, by meaning.

Interdisciplinary interventions for stunting and wasting in Zimbabwe, Zambia and Pakistan
Systems Actions to Malnutrition in All Its Forms in Chinese and South-East Asian Cities - Developing Double-Duty, Population-Level Interventions
CHild malnutrition & Adult NCD: Generating Evidence on mechanistic links to inform future policy/practice (CHANGE project)
CAPITA: Child Abuse Prevention International Training and Access
Collaborative network for adolescent nutrition and health in sub-Saharan Africa and India

Original classification

Research Grant

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