Sainsbury Wellcome Centre Core Grant Renewal
In plain English
AI plain-English summaryA single research centre in London is bringing neuroscientists and machine learning experts together under one roof to reverse-engineer how brains produce intelligence, then build artificial systems that work the same way. This matters because current AI, while powerful, does not actually think like a brain. It cannot flexibly learn, reason, or adapt the way humans do. Meanwhile, psychiatry and neurology lack a mechanistic understanding of how perception, decision-making, and goal-setting break down in conditions such as schizophrenia or dementia. The centre aims to close that gap by studying both biological and artificial intelligence side by side, using each to inform the other. If successful, the work could lead to more robust, ethical AI systems that learn efficiently and generalise well—unlike today’s data-hungry models. It could also reveal the neural basis of cognitive symptoms, pointing toward better diagnostic tools or treatments. The centre’s interdisciplinary PhD programmes and outreach across the UK and low- and middle-income countries aim to diversify the next generation of researchers. This is primarily fundamental science: understanding how brains generate cognition and behaviour. Past discoveries in this vein have seeded companies tackling health and education challenges, but the core goal is to explain intelligence itself.
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