Associated organisationsAII India Institute of Medical Sciences Bhubaneswar · Apollo Hospitals Educational and Research Foundation · Chennai Critical Care Consultants Private Limited · Chittagong Medical College Hospital · D'Or Institute for Research and Education · Doctors with Africa CUAMM · Hospital for Tropical Diseases · International Islamic University Malaysia · Jaffna Teaching Hospital · Kwame Nkrumah University of Science and Technology · Mahidol Oxford Tropical Medicine Research Unit · Makerere University · Nepal Intensive Care Research Foundation · Network for Improving Critical Care Systems and Training · Fundação Oswaldo Cruz · The Aga Khan University, Nairobi · University College London · University College London Hospitals NHS Foundation Trust · University of Amsterdam · University of Birmingham · University of British Columbia · University of Cape Town · University of Oxford · Wazir Akbar Khan Hospital · Ziauddin UniversityEurope PMC affiliations are not treated as award recipients or mapped locations.
Funding£8.3M
PeriodJan 2023 — Dec 2025
In plain English
AI plain-English summary
A network of intensive care units across Africa and Asia will pool patient data to improve survival rates for the critically ill. The COVID-19 pandemic exposed deadly gaps in critical care quality, especially in low- and middle-income countries (LMICs). Many ICUs lack the data infrastructure to track which treatments work and which do not. This project builds on existing LMIC-led registries that have already contributed to pandemic preparedness and clinical trials. The core problem is that critical care data from wealthier countries often does not apply to settings with different diseases, equipment, and staffing. If successful, the project will create a central data hub that harmonises epidemiological and treatment information across income settings for the first time. Clinicians will be able to compare outcomes and identify which care processes save lives locally. The quality improvement interventions developed here will be designed for scaling to other LMICs. The project also trains LMIC investigators to lead their own research on policy and practice, building a self-sustaining learning health system. The ultimate change is that critically ill patients in these regions receive care based on evidence from their own populations, not imported from elsewhere.
View original technical description
We envision that the project will equip an LMIC led community of practice with the infrastructure and capability to improve the quality of care for critically ill patients and healthcare providers using high value clinical and service data. The global COVID-19 pandemic has brought into focus the importance of critical care services and the impact of gaps in care quality on patient outcomes. This project builds upon the successes of our collaboration of LMIC investigator-led registries, which have contributed to data-driven health services research including pandemic preparedness and practice changing clinical trials. The outputs of this project directly align in vision with the WHO roadmap to strengthen health systems and enabling high quality LMIC research. The data research hub will provide unprecedented harmonised epidemiological and treatment data on critically ill patients comparable across income settings. The quality improvement interventions will improve care processes and generate methods scalable to other LMICs. This project will strengthen and sustain the foundations of a learning health system, whilst LMIC investigators develop the capabilities to lead research on policy, practice and population health.
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